Improved procedure for oxidations with the chromium trioxide-pyridine complex

R Ratcliffe, R Rodehorst - The Journal of Organic Chemistry, 1970 - ACS Publications
(6) WG Dauben, M. Lorber, and DS Fullerton, J. Org. Chem., 34, 3587 (1969). oxidized in our
laboratories by methylene chloride solutions of the complex, prepared by the in situ method…

Stereoselective total synthesis of the guaiazulenic sesquiterpenoids. alpha.-bulnesene and bulnesol

CH Heathcock, R Ratcliffe - Journal of the American Chemical …, 1971 - ACS Publications
(±)-a-Bulnesene (39) and (±)-bulnesol (40) have been synthesized in 17 stage routes from
the un-saturated keto alcohol 1. The key step involves solvolytic rearrangement of a decalyl …

Capacity of smart beta strategies from a transaction cost perspective

R Ratcliffe, P Miranda, A Ang - The Journal of Index Investing, 2017 - search.proquest.com
Using a transaction cost model and an assumption for the smart beta premium observed in
data, the authors estimate the capacity of a particular implementation of momentum, quality, …

Studies on the structures of imipenem, dehydropeptidase I-hydrolyzed imipenem, and related analogs

RW Ratcliffe, KJ Wildonger, L Di Michele… - The Journal of …, 1989 - ACS Publications
Dehydropeptidase I catalyzed hydrolysis of the carbapenem antibiotics imipenem (1) andthe
3-methylthio analogue 14 was examined by spectroscopic methods. The principal product …

Total synthesis of. beta.-lactam antibiotics. Epimerization of 6 (7)-aminopenicillins and cephalosporins from. alpha. to. beta.

…, NS Maciejewicz, RW Ratcliffe… - The Journal of …, 1974 - ACS Publications
The C-6 proton of 6-APA benzyl ester 3 is rendered more acidic by formation of the p-nitrobenzaldehyde
Schiff base 5. Weak bases such as diisopropylethylamine produce a moderate …

Market-driven scenarios: An approach for plausible scenario construction

…, D Greenberg, R Ratcliffe - Journal of Portfolio …, 2018 - search.proquest.com
The use of scenario analysis to better understand portfolios has increased significantly since
the global financial crisis. In this article, the authors describe a stress scenario framework …

Reduced immunotoxicity and preservation of antibacterial activity in a releasable side-chain carbapenem antibiotic

…, KJ Wildonger, TA Blizzard, FP DiNinno, RW Ratcliffe… - Science, 1999 - science.org
A carbapenem antibiotic, L-786,392, was designed so that the side chain that provides high-affinity
binding to the penicillin-binding proteins responsible for bacterial resistance was …

The synthesis of novel 8a-aza-8a-homoerythromycin derivatives via the Beckmann rearrangement of (9Z)-erythromycin A oxime

RR Wilkening, RW Ratcliffe, GA Doss… - Bioorganic & Medicinal …, 1993 - Elsevier
The (9E)-oxime of erythromycin A (1) was isomerized to the (9Z)-isomer 2 in the presence of
strong base. Stereospecific Beckmann rearrangement of the (9Z)-oxime led to a series of …

Triazolo-tetrahydrofluorenones as selective estrogen receptor beta agonists

DL Parker Jr, D Meng, RW Ratcliffe… - Bioorganic & medicinal …, 2006 - Elsevier
Several tetrahydrofluorenones with a triazole fused across C7–C8 showed high levels of
ERβ-selectivity and were found to be potent ERβ-agonists. As a class they demonstrate …

Synthesis of hydroazulenes by solvolytic rearrangement of 9-methyl-1-declyl tosylates

CH Heathcock, R Ratcliffe, J Van - The Journal of Organic …, 1972 - ACS Publications
9-Methyl-l-decalyl p-toluenesulfonates 1-4 and 3-d have been synthesized and their solvolyses
studied. Trans-fused tosylates 1 and 2 yield predominantly hydroazulenes (54, 55, 33, …