The reasoning criminal: Rational choice perspectives on offending
DB Cornish, RV Clarke - 2014 - books.google.com
The assumption that rewards and punishments influence our choices between different
courses of action underlies economic, sociological, psychological, and legal thinking about …
courses of action underlies economic, sociological, psychological, and legal thinking about …
Patient-derived xenograft models: an emerging platform for translational cancer research
Recently, there has been an increasing interest in the development and characterization of
patient-derived tumor xenograft (PDX) models for cancer research. PDX models mostly retain …
patient-derived tumor xenograft (PDX) models for cancer research. PDX models mostly retain …
Facts and recommendations about total homocysteine determinations: an expert opinion
Background: Measurement of plasma total homocysteine has become common as new
methods have been introduced. A wide range of disorders are associated with increased …
methods have been introduced. A wide range of disorders are associated with increased …
Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease
…, NC Fox, J Hardy, MCD Naranjo, P Bosco, R Clarke… - Nature …, 2013 - nature.com
Eleven susceptibility loci for late-onset Alzheimer's disease (LOAD) were identified by previous
studies; however, a large portion of the genetic risk for this disease remains unexplained. …
studies; however, a large portion of the genetic risk for this disease remains unexplained. …
Genetic studies of body mass index yield new insights for obesity biology
…, M Bruinenberg, IH Caspersen, YD Ida Chen, R Clarke… - Nature, 2015 - nature.com
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of
obesity better, here we conduct a genome-wide association study and Metabochip meta-…
obesity better, here we conduct a genome-wide association study and Metabochip meta-…
Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index
…, YDI Chen, CM Chen, PS Chines, R Clarke… - Nature …, 2010 - nature.com
Obesity is globally prevalent and highly heritable, but its underlying genetic factors remain
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …
largely elusive. To identify genetic loci for obesity susceptibility, we examined associations …
New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk
…, G Charpentier, YDI Chen, P Chines, R Clarke… - Nature …, 2010 - nature.com
Levels of circulating glucose are tightly regulated. To identify new loci influencing glycemic
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
traits, we performed meta-analyses of 21 genome-wide association studies informative for …
[HTML][HTML] Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study
Background High plasma HDL cholesterol is associated with reduced risk of myocardial
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are …
infarction, but whether this association is causal is unclear. Exploiting the fact that genotypes are …
Genetic variants in novel pathways influence blood pressure and cardiovascular disease risk
…, DA Lawlor, JP Beilby, RW Lawrence, R Clarke… - Nature, 2011 - nature.com
Blood pressure is a heritable trait 1 influenced by several biological pathways and responsive
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …
to environmental stimuli. Over one billion people worldwide have hypertension (≥140 mm …
Newly identified loci that influence lipid concentrations and risk of coronary artery disease
…, AU Jackson, A Scuteri, LL Bonnycastle, R Clarke… - Nature …, 2008 - nature.com
To identify genetic variants influencing plasma lipid concentrations, we first used genotype
imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals …
imputation and meta-analysis to combine three genome-wide scans totaling 8,816 individuals …