Mesenchymal stromal cells (MSC) have gained immense attraction in regenerative medicine,
tissue engineering, and immunotherapy. This is based on their differentiation potential and …

The molecular mechanisms specifying the dendritic morphology of different neuronal
subtypes are poorly understood. Here we demonstrate that the bHLH transcription factor …

… Philip Mattar now offers the first full-length biography of this intriguing figure, weaving a
fresh and objective revisionist account. Mattar clarifies al-Husayni's role in the politics of …

… Olivier Britz and Pierre Mattar have contributed equally to this work. The two senior
authors, Francçois Guillemot and Carol Schuurmans, have contributed equally to this work. …

Autoimmune diseases such as multiple sclerosis are characterized by complex genetic traits
and pathomechanisms that translate into clinical heterogeneity. This wide heterogeneity of …

… We propose that Ikzf1 and Casz1 have this role in mammalian RPCs (Figure 4P). Such a
model is consistent with observations that loss or gain of function of either Ikzf1 or Casz1 alters …

Obesity is currently a serious worldwide public health problem, reaching pandemic levels.
For decades, dietary and behavioral approaches have failed to prevent this disease from …

… Pierre Mattar … We thank David Picketts as well as Mattar lab members for their input
and discussions. PM holds the Gladys and Lorna J. Wood Chair for Research in Vision. …

Neural cell fate specification is well understood in the embryonic cerebral cortex, where the
proneural genes Neurog2 and Ascl1 are key cell fate determinants. What is less well …

Several transcription factors are essential determinants of a cortical projection neuron identity,
but their mode of action (instructive versus permissive) and downstream genetic cascades …