With emphasis on the simple plant location problem (SPLP), we consider an important
family of discrete, deterministic, single-criterion, NP-hard, and widely applicable optimization …

A review of the recent work on polymer matrix nanocomposites is presented. This review is
not intended to be comprehensive, but provides an overview of the processing techniques …

Regional patterns of present-day tectonic stress can be used to evaluate the forces acting
on the lithosphere and to investigate intraplate seismicity. Most intraplate regions are …

There is currently tremendous interest in the possibility of using genome-wide association
mapping to identify genes responsible for natural variation, particularly for human disease …

Background Nosocomial infections due to Pseudomonas aeruginosa have been well described,
but the environmental reservoir of the organism varies. We conducted an epidemiologic …

Invasion, metastasis and therapy resistance are the major cause of cancer‐associated deaths,
and the EMT ‐inducing transcription factor ZEB 1 is a crucial stimulator of these processes…

Over the last 20 years, policy appraisal has emerged as a popular topic for discussion
amongst policy-makers and academics alike. Much research effort has been devoted to …

C4 grasses are among the most productive plants and most promising cellulosic biofuel
feedstocks. Successful implementation of cellulosic biofuel feedstocks will depend on the …

Glioblastoma multiforme (GBM) is a lethal brain tumour in adults and children. However,
DNA copy number and gene expression signatures indicate differences between adult and …

Glioblastoma (GBM) is a brain tumor that carries a dismal prognosis and displays considerable
heterogeneity. We have recently identified recurrent H3F3A mutations affecting two …